Accessibility is not an especially familiar concept in the computing world. Most of us encounter the idea of accessibility often enough by way of special vehicle parking spaces, ramps, braille signage, beeping crosswalks, and so on. Improving accessibility is more than a courtesy, it is an accepted and vital goal of any advanced society.
Johnson, Duff. PlanetPDF. Design>Document Design>Accessibility>Adobe Acrobat
Facts and Opinions About PDF Accessibility
PDF accessibility is not as straightforward as HTML accessibility. But it can be done, if you put the same care into marking up your PDFs that you put into marking up websites. Joe Clark tells all.
Clark, Joe. List Apart, A (2005). Design>Document Design>Accessibility>Adobe Acrobat
Reading Expository Text on a Computer Screen 
Issues of legibility, restricted screen space, and the resulting effects on reader efficiency have hampered efforts to bring expository text to the computer screen. Previous research focused on character-based displays, a technology that is rapidly being supplanted by equipment capable of improved resolution and visual symbol generation. These issues, which affect both authors and readers, need to be investigated in light of current screen and user interface technology. It may well be that linear expository texts are easily adaptable to contemporary computer screens.
Ham, Eardley L. STC Proceedings (1994). Design>Document Design>Accessibility
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