PDF Can Comply With Section 508. Now It's Your Move

A blind person cannot read from a screen any more than from a printed page. Technologies nonetheless exist that allow blind and other disabled users impressively full-featured access to documents. To be accessible, however, the document contents must be available to these so-called 'assistive' technologies.

Johnson, Duff. PlanetPDF (2003). Articles>Accessibility>Adobe Acrobat>Section 508

PDFs and Section 508: Compliance, Accessibility, and Usability  

This paper addresses limitations and problematic issues of usability and accessibility involved in the creation and use of Adobe Acrobat PDF files for people with visual impairments who use screen readers as an assistive device. In some cases, due to technological limitations, PDF documents can present information incorrectly to such persons. A document which is accessibility compliant may then not be fully usable by individuals with visual impairments. The lack of specific guidelines for accessible PDF documents complicates the issue, though a series of W3C PDF Checkpoints provides some guidance. Problematic issues discussed include footnotes, special characters and formats, acronyms and abbreviations, and tables.

Dolin, Samantha and Jane L. Willig. STC Proceedings (2004). Articles>Accessibility>Adobe Acrobat>Section 508