The study reported here assessed the effects of isolation on attention. Is it true, in other words, that isolating an element in a visual display—moving an element away from other elements and surrounding it with white space—will inspire a greater allocation of attentional resources to the isolated element than to other elements on a page or screen?
Williams, Thomas R., Christopher Mulligan, Kent Koprowicz, Jamie Miller, Christy Reimann and Da-Shin Wang. Technical Communication Online (2005). Articles>Usability>Human Computer Interaction
Guidelines for Designing and Evaluating the Display of Information on the Web

These guidelines are intended to assist Web designers, authors, and editors in their efforts to create Web pages that effectively reveal—rather than obscure or confuse—the information they are trying to present. These guidelines are also intended to be used to assist in the evaluation of existing Web sites. Of course, the design of a Web site can, to some degree, be modified by the user or by the characteristics of the browser or monitor enlisted to display it. The guidelines, consequently, acknowledge that in a very real sense, users may also assume the role of designer. The guidelines, therefore, are also intended to help users make informed decisions about how to make a display easier to use.
Williams, Thomas R. Technical Communication Online (2000). Articles>Web Design>Assessment>Visual Rhetoric
Visual Disciminability of Headings in Text

Headings in text provide critical symbols that help a reader discern a writer's structural treatment of a topic.
Williams, Thomas R. and Jan H. Spyridakis. IEEE Transactions on Professional Communication (1992). Design>Typography
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