Content Management and the Electronic Common Technical Document (eCTD)
http://rockleybulletin.com/technologycorner_comments.php?id=56_0_6_0_C

Rockley, Ann
Rockley Group, The
2004

Abstract:

The XML eCTD DTD (Document Type Definition) defines the overall structure of the submission. The purpose of the XML backbone is two-fold: (1) to manage meta-data for the entire submission and each document within the submission and (2) to constitute a comprehensive table of contents and provide corresponding navigation aids.